A gene responsible for the formation of enamel was discovered A team of researchers headed by Professor Dr. Thimios Mitsiadis at the University of Zurich, Switzerland, has identified a gene that is responsible for the formation of enamel, which is the basic component of the teeth. Experiments performed on mice deleted the transcription factor Tbx1, a gene that plays a major role in various human deformities (heart, thymus gland, parathyroid, face, and teeth) associated with DiGeorge syndrome.
Could dental treatment benefit in the future from this revolutionary study?
The definitive answer is “yes”. Understanding the genetic code that controls the growth of teeth and their repair, will allow us to operate and create new products to replace tissue for worn and unhealthy teeth.
Is it possible for dentists to use stem cells to stimulate the growth of new enamel?
“This is the biggest challenge in the dental engineering industry. In some cases of genetic abnormalities of the teeth, in the regeneration and repair of the teeth there is the possibility of dealing with the stem cells. Inactive dental stem cells could be used in the future for local tissue transplantation in dentistry, ”explains Professor Mitsiadis.
